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Nificard Brand names, Nificard Analogs

Nificard Brand Names Mixture

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Nificard Chemical_Formula


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Nificard msds (material safety sheet)

Nificard MSDS

Nificard Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Nificard Molecular Weight

346.335 g/mol

Nificard Melting Point

172 - 174 oC

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Nificard Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Nificard Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Nificard Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Nificard Absorption

Rapidly and fully absorbed following oral administration.

Nificard side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

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Nificard Organisms Affected

Humans and other mammals