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Kordafen Brand names, Kordafen Analogs

Kordafen Brand Names Mixture

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Kordafen Chemical_Formula


Kordafen RX_link


Kordafen fda sheet

Kordafen FDA

Kordafen msds (material safety sheet)

Kordafen MSDS

Kordafen Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Kordafen Molecular Weight

346.335 g/mol

Kordafen Melting Point

172 - 174 oC

Kordafen H2O Solubility


Kordafen State


Kordafen LogP


Kordafen Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Kordafen Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Kordafen Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Kordafen Absorption

Rapidly and fully absorbed following oral administration.

Kordafen side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Kordafen Patient Information

Kordafen Organisms Affected

Humans and other mammals