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Adalat Brand names, Adalat Analogs

Adalat Brand Names Mixture

  • No information avaliable

Adalat Chemical_Formula

C17H18N2O6

Adalat RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Adalat fda sheet

Adalat FDA

Adalat msds (material safety sheet)

Adalat MSDS

Adalat Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Adalat Molecular Weight

346.335 g/mol

Adalat Melting Point

172 - 174 oC

Adalat H2O Solubility

Insoluble

Adalat State

Solid

Adalat LogP

2.343

Adalat Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Adalat Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Adalat Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Adalat Absorption

Rapidly and fully absorbed following oral administration.

Adalat side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Adalat Patient Information

Adalat Organisms Affected

Humans and other mammals