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Megalat Brand names, Megalat Analogs

Megalat Brand Names Mixture

  • No information avaliable

Megalat Chemical_Formula


Megalat RX_link

Megalat fda sheet

Megalat FDA

Megalat msds (material safety sheet)

Megalat MSDS

Megalat Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Megalat Molecular Weight

346.335 g/mol

Megalat Melting Point

172 - 174 oC

Megalat H2O Solubility


Megalat State


Megalat LogP


Megalat Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Megalat Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Megalat Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Megalat Absorption

Rapidly and fully absorbed following oral administration.

Megalat side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Megalat Patient Information

Megalat Organisms Affected

Humans and other mammals