Adapine
Adapine Brand names, Adapine Analogs
- Adalat
- Adalat 10
- Adalat 20
- Adalat 5
- Adalat CC
- Adalat CR
- Adalat Crono
- Adalat Ft
- Adalat Gits
- Adalat Gits 30
- Adalat LA
- Adalat LP
- Adalat Oros
- Adalat PA
- Adalat Retard
- Adalate
- Adapine
- Adapress
- Alat
- Aldipin
- Alfadal
- Alonix
- Alonix S
- Alpha-Nifedipine Retard
- Angipec
- Anifed
- Anpine
- Apo-Nifed
- Aprical
- Bonacid
- Calcibloc
- Calcigard
- Calcilat
- Camont
- Cardifen
- Cardilat
- Cardilate
- Cardionorm
- Chronadalate
- Chronadalate Lp
- Citilat
- Coracten
- Coral
- Cordafen
- Cordaflex
- Cordalat
- Cordicant
- Cordilan
- Cordipin
- Corinfar
- Corotrend
- Corynphar
- Depin
- Dignokonstant
- Dilafed
- Dilcor
- Dipinkor
- Duranifin
- Ecodipi
- Ecodipin
- Ecodipin E
- Fedcor
- Fedcor Retard
- Fenamon
- Fenamon Sr
- Fenihidin
- Fenihidine
- Glopir
- Hadipin
- Hexadilat
- Introcar
- Kordafen
- Macorel
- Megalat
- Myogard
- N1fedilat
- Nedipin
- Nicardia
- Nifangin
- Nifar
- Nifdemin
- Nifebene
- Nifecard
- Nifecor
- Nifedepat
- Nifedicor
- Nifedin
- Nifedine
- Nifedipine Retard
- Nifedipres
- Nifedirex LP
- Nifelan
- Nifelat
- Nifelat Q
- Nifelate
- Nifensar XL
- Nificard
- Nifidine
- Nifipen
- Niphedipine
- Orix
- Oxcord
- Pidilat
- Procardia
- Procardia XL
- Sepamit
- Tibricol
- Zenusin
Adapine Brand Names Mixture
- No information avaliable
Adapine Chemical_Formula
C17H18N2O6
Adapine RX_link
http://www.rxlist.com/cgi/generic2/nifedip.htm
Adapine fda sheet
Adapine msds (material safety sheet)
Adapine Synthesis Reference
Bossert, Vater, U.S. Pat. 3,485,847 (1969)
Adapine Molecular Weight
346.335 g/mol
Adapine Melting Point
172 - 174 oC
Adapine H2O Solubility
Insoluble
Adapine State
Solid
Adapine LogP
2.343
Adapine Dosage Forms
Capsule; Tablet; Tablet (extended-release)
Adapine Indication
For the management of vasospastic angina, chronic stable angina and hypertension.
Adapine Pharmacology
Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.
Adapine Absorption
Rapidly and fully absorbed following oral administration.
Adapine side effects and Toxicity
Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)
Adapine Patient Information
Adapine Organisms Affected
Humans and other mammals
