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Adalate Brand names, Adalate Analogs

Adalate Brand Names Mixture

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Adalate Chemical_Formula


Adalate RX_link

Adalate fda sheet

Adalate FDA

Adalate msds (material safety sheet)

Adalate MSDS

Adalate Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Adalate Molecular Weight

346.335 g/mol

Adalate Melting Point

172 - 174 oC

Adalate H2O Solubility


Adalate State


Adalate LogP


Adalate Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Adalate Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Adalate Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Adalate Absorption

Rapidly and fully absorbed following oral administration.

Adalate side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Adalate Patient Information

Adalate Organisms Affected

Humans and other mammals