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Cordipin Brand names, Cordipin Analogs

Cordipin Brand Names Mixture

  • No information avaliable

Cordipin Chemical_Formula

C17H18N2O6

Cordipin RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Cordipin fda sheet

Cordipin FDA

Cordipin msds (material safety sheet)

Cordipin MSDS

Cordipin Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Cordipin Molecular Weight

346.335 g/mol

Cordipin Melting Point

172 - 174 oC

Cordipin H2O Solubility

Insoluble

Cordipin State

Solid

Cordipin LogP

2.343

Cordipin Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Cordipin Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Cordipin Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Cordipin Absorption

Rapidly and fully absorbed following oral administration.

Cordipin side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Cordipin Patient Information

Cordipin Organisms Affected

Humans and other mammals