Alonix

Alonix Brand names, Alonix Analogs

Alonix Brand Names Mixture

No information avaliable

Alonix Chemical_Formula

C₁₇H₁₈N₂O₆

Alonix RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Alonix fda sheet

Alonix FDA

Alonix msds (material safety sheet)

Alonix MSDS

Alonix Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Alonix Molecular Weight

346.335 g/mol

Alonix Melting Point

172 - 174 ^oC

Alonix H₂O Solubility

Insoluble

Alonix State

Solid

Alonix LogP

2.343

Alonix Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Alonix Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Alonix Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Alonix Absorption

Rapidly and fully absorbed following oral administration.

Alonix side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD₅₀=494 mg/kg (orally in mice); LD₅₀=1022 mg/kg (orally in rats)

Alonix Patient Information

Alonix Organisms Affected

Humans and other mammals