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Corinfar Brand names, Corinfar Analogs

Corinfar Brand Names Mixture

  • No information avaliable

Corinfar Chemical_Formula

C17H18N2O6

Corinfar RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Corinfar fda sheet

Corinfar FDA

Corinfar msds (material safety sheet)

Corinfar MSDS

Corinfar Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Corinfar Molecular Weight

346.335 g/mol

Corinfar Melting Point

172 - 174 oC

Corinfar H2O Solubility

Insoluble

Corinfar State

Solid

Corinfar LogP

2.343

Corinfar Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Corinfar Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Corinfar Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Corinfar Absorption

Rapidly and fully absorbed following oral administration.

Corinfar side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Corinfar Patient Information

Corinfar Organisms Affected

Humans and other mammals