Nifidine en es it fr

Nifidine Brand names, Nifidine Analogs

Nifidine Brand Names Mixture

  • No information avaliable

Nifidine Chemical_Formula


Nifidine RX_link

Nifidine fda sheet

Nifidine FDA

Nifidine msds (material safety sheet)

Nifidine MSDS

Nifidine Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Nifidine Molecular Weight

346.335 g/mol

Nifidine Melting Point

172 - 174 oC

Nifidine H2O Solubility


Nifidine State


Nifidine LogP


Nifidine Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Nifidine Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Nifidine Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Nifidine Absorption

Rapidly and fully absorbed following oral administration.

Nifidine side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Nifidine Patient Information

Nifidine Organisms Affected

Humans and other mammals