Chronadalate en es it fr

Chronadalate Brand names, Chronadalate Analogs

Chronadalate Brand Names Mixture

  • No information avaliable

Chronadalate Chemical_Formula


Chronadalate RX_link

Chronadalate fda sheet

Chronadalate FDA

Chronadalate msds (material safety sheet)

Chronadalate MSDS

Chronadalate Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Chronadalate Molecular Weight

346.335 g/mol

Chronadalate Melting Point

172 - 174 oC

Chronadalate H2O Solubility


Chronadalate State


Chronadalate LogP


Chronadalate Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Chronadalate Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Chronadalate Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Chronadalate Absorption

Rapidly and fully absorbed following oral administration.

Chronadalate side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Chronadalate Patient Information

Chronadalate Organisms Affected

Humans and other mammals