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Nifedin Brand names, Nifedin Analogs

Nifedin Brand Names Mixture

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Nifedin Chemical_Formula


Nifedin RX_link

Nifedin fda sheet

Nifedin FDA

Nifedin msds (material safety sheet)

Nifedin MSDS

Nifedin Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Nifedin Molecular Weight

346.335 g/mol

Nifedin Melting Point

172 - 174 oC

Nifedin H2O Solubility


Nifedin State


Nifedin LogP


Nifedin Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Nifedin Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Nifedin Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Nifedin Absorption

Rapidly and fully absorbed following oral administration.

Nifedin side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Nifedin Patient Information

Nifedin Organisms Affected

Humans and other mammals