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Cordalat Brand names, Cordalat Analogs

Cordalat Brand Names Mixture

  • No information avaliable

Cordalat Chemical_Formula

C17H18N2O6

Cordalat RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Cordalat fda sheet

Cordalat FDA

Cordalat msds (material safety sheet)

Cordalat MSDS

Cordalat Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Cordalat Molecular Weight

346.335 g/mol

Cordalat Melting Point

172 - 174 oC

Cordalat H2O Solubility

Insoluble

Cordalat State

Solid

Cordalat LogP

2.343

Cordalat Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Cordalat Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Cordalat Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Cordalat Absorption

Rapidly and fully absorbed following oral administration.

Cordalat side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Cordalat Patient Information

Cordalat Organisms Affected

Humans and other mammals