Nifangin

Nifangin Brand names, Nifangin Analogs

Nifangin Brand Names Mixture

No information avaliable

Nifangin Chemical_Formula

C₁₇H₁₈N₂O₆

Nifangin RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Nifangin fda sheet

Nifangin FDA

Nifangin msds (material safety sheet)

Nifangin MSDS

Nifangin Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Nifangin Molecular Weight

346.335 g/mol

Nifangin Melting Point

172 - 174 ^oC

Nifangin H₂O Solubility

Insoluble

Nifangin State

Solid

Nifangin LogP

2.343

Nifangin Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Nifangin Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Nifangin Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Nifangin Absorption

Rapidly and fully absorbed following oral administration.

Nifangin side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD₅₀=494 mg/kg (orally in mice); LD₅₀=1022 mg/kg (orally in rats)

Nifangin Patient Information

Nifangin Organisms Affected

Humans and other mammals