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Nifedipres Brand names, Nifedipres Analogs

Nifedipres Brand Names Mixture

  • No information avaliable

Nifedipres Chemical_Formula


Nifedipres RX_link

Nifedipres fda sheet

Nifedipres FDA

Nifedipres msds (material safety sheet)

Nifedipres MSDS

Nifedipres Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Nifedipres Molecular Weight

346.335 g/mol

Nifedipres Melting Point

172 - 174 oC

Nifedipres H2O Solubility


Nifedipres State


Nifedipres LogP


Nifedipres Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Nifedipres Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Nifedipres Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Nifedipres Absorption

Rapidly and fully absorbed following oral administration.

Nifedipres side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Nifedipres Patient Information

Nifedipres Organisms Affected

Humans and other mammals