Adalat 5

Adalat 5 Brand names, Adalat 5 Analogs

Adalat 5 Brand Names Mixture

No information avaliable

Adalat 5 Chemical_Formula

C₁₇H₁₈N₂O₆

Adalat 5 RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Adalat 5 fda sheet

Adalat_5 FDA

Adalat 5 msds (material safety sheet)

Adalat_5 MSDS

Adalat 5 Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Adalat 5 Molecular Weight

346.335 g/mol

Adalat 5 Melting Point

172 - 174 ^oC

Adalat 5 H₂O Solubility

Insoluble

Adalat 5 State

Solid

Adalat 5 LogP

2.343

Adalat 5 Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Adalat 5 Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Adalat 5 Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Adalat 5 Absorption

Rapidly and fully absorbed following oral administration.

Adalat 5 side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD₅₀=494 mg/kg (orally in mice); LD₅₀=1022 mg/kg (orally in rats)

Adalat 5 Patient Information

Adalat 5 Organisms Affected

Humans and other mammals