General

Synonyms: (1R-trans)-1,2-cyclohexanediamine platinum complex, oxalato(trans-l-1,2-cyclohexanediamine)platinum (II), oxalatoplatin, oxalatoplatinum, oxaliplatin
Use: chemotherapy drug
Molecular formula: C₈H₁₄N₂O₄Pt
CAS No: 61825-94-3
EINECS No:

Physical data

Appearance: solid
Melting point:
Boiling point:
Vapour density:
Vapour pressure:
Density (g cm^-3):
Flash point:
Explosion limits:
Autoignition temperature:
Water solubility:

Stability

Stable. Store cool. Incompatible with oxidizing agents.

Toxicology

Irritant. May cause sensitization by skin contact or if inhaled. Limited evidence of a carcinogenic effect. May cause cumulative renal toxicity.

Toxicity data
(The meaning of any toxicological abbreviations which appear in this section is given here.)
IPR-RAT LD50 14.3 mg kg^-1
IPR-MUS LD50 19.8 mg kg^-1

Risk phrases
(The meaning of any risk phrases which appear in this section is given here.)
R36 R37 R38 R40 R42 R43.

Transport information

(The meaning of any UN hazard codes which appear in this section is given here.)
Non-hazardous for air, sea and road freight.

Personal protection

Safety glasses, gloves. Note that platinum compounds can cause sensitization in susceptible subjects which, in extreme cases, can be quite disabling. If signs of sensitization appear, discontinue laboratory use.

Safety phrases
(The meaning of any safety phrases which appear in this section is given here.)
S26 S36.

[Return to Physical & Theoretical Chemistry Lab. Safety home page.]

This information was last updated on August 31, 2004. We have tried to make it as accurate and useful as possible, but can take no responsibility for its use, misuse, or accuracy. We have not verified this information, and cannot guarantee that it is up-to-date.