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E-Pam Brand names, E-Pam Analogs

E-Pam Brand Names Mixture

  • No information avaliable

E-Pam Chemical_Formula


E-Pam RX_link


E-Pam fda sheet

E-Pam msds (material safety sheet)


E-Pam Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

E-Pam Molecular Weight

284.74 g/mol

E-Pam Melting Point


E-Pam H2O Solubility

Slightly soluble (50 mg/L)

E-Pam State


E-Pam LogP


E-Pam Dosage Forms

Tablets; Injectable solution

E-Pam Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

E-Pam Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

E-Pam Absorption

Essentially complete, with a bioavailability of 93%.

E-Pam side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

E-Pam Patient Information

E-Pam Organisms Affected

Humans and other mammals