Lamra

Lamra Brand names, Lamra Analogs

Lamra Brand Names Mixture

No information avaliable

Lamra Chemical_Formula

C₁₆H₁₃ClN₂O

Lamra RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Lamra fda sheet

Lamra msds (material safety sheet)

Lamra MSDS

Lamra Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Lamra Molecular Weight

284.74 g/mol

Lamra Melting Point

125-126^oC

Lamra H₂O Solubility

Slightly soluble (50 mg/L)

Lamra State

solid

Lamra LogP

2.988

Lamra Dosage Forms

Tablets; Injectable solution

Lamra Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Lamra Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Lamra Absorption

Essentially complete, with a bioavailability of 93%.

Lamra side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Lamra Patient Information

Lamra Organisms Affected

Humans and other mammals