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Diastat Brand names, Diastat Analogs

Diastat Brand Names Mixture

  • No information avaliable

Diastat Chemical_Formula


Diastat RX_link


Diastat fda sheet

Diastat msds (material safety sheet)

Diastat MSDS

Diastat Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Diastat Molecular Weight

284.74 g/mol

Diastat Melting Point


Diastat H2O Solubility

Slightly soluble (50 mg/L)

Diastat State


Diastat LogP


Diastat Dosage Forms

Tablets; Injectable solution

Diastat Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Diastat Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Diastat Absorption

Essentially complete, with a bioavailability of 93%.

Diastat side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Diastat Patient Information

Diastat Organisms Affected

Humans and other mammals