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Pacitran Brand names, Pacitran Analogs

Pacitran Brand Names Mixture

  • No information avaliable

Pacitran Chemical_Formula

C16H13ClN2O

Pacitran RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Pacitran fda sheet

Pacitran msds (material safety sheet)

Pacitran MSDS

Pacitran Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Pacitran Molecular Weight

284.74 g/mol

Pacitran Melting Point

125-126oC

Pacitran H2O Solubility

Slightly soluble (50 mg/L)

Pacitran State

solid

Pacitran LogP

2.988

Pacitran Dosage Forms

Tablets; Injectable solution

Pacitran Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Pacitran Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Pacitran Absorption

Essentially complete, with a bioavailability of 93%.

Pacitran side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Pacitran Patient Information

Pacitran Organisms Affected

Humans and other mammals