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An-Ding Brand names, An-Ding Analogs

An-Ding Brand Names Mixture

  • No information avaliable

An-Ding Chemical_Formula

C16H13ClN2O

An-Ding RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

An-Ding fda sheet

An-Ding msds (material safety sheet)

An-Ding MSDS

An-Ding Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

An-Ding Molecular Weight

284.74 g/mol

An-Ding Melting Point

125-126oC

An-Ding H2O Solubility

Slightly soluble (50 mg/L)

An-Ding State

solid

An-Ding LogP

2.988

An-Ding Dosage Forms

Tablets; Injectable solution

An-Ding Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

An-Ding Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

An-Ding Absorption

Essentially complete, with a bioavailability of 93%.

An-Ding side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

An-Ding Patient Information

An-Ding Organisms Affected

Humans and other mammals