Assival

Assival Brand names, Assival Analogs

Assival Brand Names Mixture

No information avaliable

Assival Chemical_Formula

C₁₆H₁₃ClN₂O

Assival RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Assival fda sheet

Assival msds (material safety sheet)

Assival MSDS

Assival Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Assival Molecular Weight

284.74 g/mol

Assival Melting Point

125-126^oC

Assival H₂O Solubility

Slightly soluble (50 mg/L)

Assival State

solid

Assival LogP

2.988

Assival Dosage Forms

Tablets; Injectable solution

Assival Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Assival Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Assival Absorption

Essentially complete, with a bioavailability of 93%.

Assival side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Assival Patient Information

Assival Organisms Affected

Humans and other mammals