Condition en es it fr

Condition Brand names, Condition Analogs

Condition Brand Names Mixture

  • No information avaliable

Condition Chemical_Formula


Condition RX_link

Condition fda sheet

Condition msds (material safety sheet)

Condition MSDS

Condition Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Condition Molecular Weight

284.74 g/mol

Condition Melting Point


Condition H2O Solubility

Slightly soluble (50 mg/L)

Condition State


Condition LogP


Condition Dosage Forms

Tablets; Injectable solution

Condition Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Condition Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Condition Absorption

Essentially complete, with a bioavailability of 93%.

Condition side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Condition Patient Information

Condition Organisms Affected

Humans and other mammals