Diazemuls

Diazemuls Brand names, Diazemuls Analogs

Diazemuls Brand Names Mixture

No information avaliable

Diazemuls Chemical_Formula

C₁₆H₁₃ClN₂O

Diazemuls RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Diazemuls fda sheet

Diazemuls msds (material safety sheet)

Diazemuls MSDS

Diazemuls Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Diazemuls Molecular Weight

284.74 g/mol

Diazemuls Melting Point

125-126^oC

Diazemuls H₂O Solubility

Slightly soluble (50 mg/L)

Diazemuls State

solid

Diazemuls LogP

2.988

Diazemuls Dosage Forms

Tablets; Injectable solution

Diazemuls Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Diazemuls Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Diazemuls Absorption

Essentially complete, with a bioavailability of 93%.

Diazemuls side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Diazemuls Patient Information

Diazemuls Organisms Affected

Humans and other mammals