Gewacalm

Gewacalm Brand names, Gewacalm Analogs

Gewacalm Brand Names Mixture

No information avaliable

Gewacalm Chemical_Formula

C₁₆H₁₃ClN₂O

Gewacalm RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Gewacalm fda sheet

Gewacalm msds (material safety sheet)

Gewacalm MSDS

Gewacalm Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Gewacalm Molecular Weight

284.74 g/mol

Gewacalm Melting Point

125-126^oC

Gewacalm H₂O Solubility

Slightly soluble (50 mg/L)

Gewacalm State

solid

Gewacalm LogP

2.988

Gewacalm Dosage Forms

Tablets; Injectable solution

Gewacalm Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Gewacalm Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Gewacalm Absorption

Essentially complete, with a bioavailability of 93%.

Gewacalm side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Gewacalm Patient Information

Gewacalm Organisms Affected

Humans and other mammals