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Cercine Brand names, Cercine Analogs

Cercine Brand Names Mixture

  • No information avaliable

Cercine Chemical_Formula

C16H13ClN2O

Cercine RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Cercine fda sheet

Cercine msds (material safety sheet)

Cercine MSDS

Cercine Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Cercine Molecular Weight

284.74 g/mol

Cercine Melting Point

125-126oC

Cercine H2O Solubility

Slightly soluble (50 mg/L)

Cercine State

solid

Cercine LogP

2.988

Cercine Dosage Forms

Tablets; Injectable solution

Cercine Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Cercine Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Cercine Absorption

Essentially complete, with a bioavailability of 93%.

Cercine side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Cercine Patient Information

Cercine Organisms Affected

Humans and other mammals