Valitran

Valitran Brand names, Valitran Analogs

Valitran Brand Names Mixture

No information avaliable

Valitran Chemical_Formula

C₁₆H₁₃ClN₂O

Valitran RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Valitran fda sheet

Valitran msds (material safety sheet)

Valitran MSDS

Valitran Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Valitran Molecular Weight

284.74 g/mol

Valitran Melting Point

125-126^oC

Valitran H₂O Solubility

Slightly soluble (50 mg/L)

Valitran State

solid

Valitran LogP

2.988

Valitran Dosage Forms

Tablets; Injectable solution

Valitran Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Valitran Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Valitran Absorption

Essentially complete, with a bioavailability of 93%.

Valitran side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Valitran Patient Information

Valitran Organisms Affected

Humans and other mammals