Duxen

Duxen Brand names, Duxen Analogs

Duxen Brand Names Mixture

No information avaliable

Duxen Chemical_Formula

C₁₆H₁₃ClN₂O

Duxen RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Duxen fda sheet

Duxen msds (material safety sheet)

Duxen MSDS

Duxen Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Duxen Molecular Weight

284.74 g/mol

Duxen Melting Point

125-126^oC

Duxen H₂O Solubility

Slightly soluble (50 mg/L)

Duxen State

solid

Duxen LogP

2.988

Duxen Dosage Forms

Tablets; Injectable solution

Duxen Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Duxen Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Duxen Absorption

Essentially complete, with a bioavailability of 93%.

Duxen side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Duxen Patient Information

Duxen Organisms Affected

Humans and other mammals