Q-Pam Relanium
Brand names,
Q-Pam Relanium
Analogs
Q-Pam Relanium
Brand Names Mixture
Q-Pam Relanium
Chemical_Formula
C16H13ClN2O
Q-Pam Relanium
RX_link
http://www.rxlist.com/cgi/generic/diazepam.htm
Q-Pam Relanium
fda sheet
Q-Pam Relanium
msds (material safety sheet)
Q-Pam Relanium
Synthesis Reference
Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)
Q-Pam Relanium
Molecular Weight
284.74 g/mol
Q-Pam Relanium
Melting Point
125-126oC
Q-Pam Relanium
H2O Solubility
Slightly soluble (50 mg/L)
Q-Pam Relanium
State
solid
Q-Pam Relanium
LogP
2.988
Q-Pam Relanium
Dosage Forms
Tablets; Injectable solution
Q-Pam Relanium
Indication
Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.
Q-Pam Relanium
Pharmacology
Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.
Q-Pam Relanium
Absorption
Essentially complete, with a bioavailability of 93%.
Q-Pam Relanium
side effects and Toxicity
Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.
Q-Pam Relanium
Patient Information
Q-Pam Relanium
Organisms Affected
Humans and other mammals