Sibazone en es it fr

Sibazone Brand names, Sibazone Analogs

Sibazone Brand Names Mixture

  • No information avaliable

Sibazone Chemical_Formula


Sibazone RX_link

Sibazone fda sheet

Sibazone msds (material safety sheet)

Sibazone MSDS

Sibazone Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Sibazone Molecular Weight

284.74 g/mol

Sibazone Melting Point


Sibazone H2O Solubility

Slightly soluble (50 mg/L)

Sibazone State


Sibazone LogP


Sibazone Dosage Forms

Tablets; Injectable solution

Sibazone Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Sibazone Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Sibazone Absorption

Essentially complete, with a bioavailability of 93%.

Sibazone side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Sibazone Patient Information

Sibazone Organisms Affected

Humans and other mammals