Setonil

Setonil Brand names, Setonil Analogs

Setonil Brand Names Mixture

No information avaliable

Setonil Chemical_Formula

C₁₆H₁₃ClN₂O

Setonil RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Setonil fda sheet

Setonil msds (material safety sheet)

Setonil MSDS

Setonil Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Setonil Molecular Weight

284.74 g/mol

Setonil Melting Point

125-126^oC

Setonil H₂O Solubility

Slightly soluble (50 mg/L)

Setonil State

solid

Setonil LogP

2.988

Setonil Dosage Forms

Tablets; Injectable solution

Setonil Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Setonil Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Setonil Absorption

Essentially complete, with a bioavailability of 93%.

Setonil side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Setonil Patient Information

Setonil Organisms Affected

Humans and other mammals