Alupram

Alupram Brand names, Alupram Analogs

Alupram Brand Names Mixture

No information avaliable

Alupram Chemical_Formula

C₁₆H₁₃ClN₂O

Alupram RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Alupram fda sheet

Alupram msds (material safety sheet)

Alupram MSDS

Alupram Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Alupram Molecular Weight

284.74 g/mol

Alupram Melting Point

125-126^oC

Alupram H₂O Solubility

Slightly soluble (50 mg/L)

Alupram State

solid

Alupram LogP

2.988

Alupram Dosage Forms

Tablets; Injectable solution

Alupram Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Alupram Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Alupram Absorption

Essentially complete, with a bioavailability of 93%.

Alupram side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Alupram Patient Information

Alupram Organisms Affected

Humans and other mammals