Quiatril

Quiatril Brand names, Quiatril Analogs

Quiatril Brand Names Mixture

No information avaliable

Quiatril Chemical_Formula

C₁₆H₁₃ClN₂O

Quiatril RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Quiatril fda sheet

Quiatril msds (material safety sheet)

Quiatril MSDS

Quiatril Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Quiatril Molecular Weight

284.74 g/mol

Quiatril Melting Point

125-126^oC

Quiatril H₂O Solubility

Slightly soluble (50 mg/L)

Quiatril State

solid

Quiatril LogP

2.988

Quiatril Dosage Forms

Tablets; Injectable solution

Quiatril Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Quiatril Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Quiatril Absorption

Essentially complete, with a bioavailability of 93%.

Quiatril side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Quiatril Patient Information

Quiatril Organisms Affected

Humans and other mammals