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Sibazon Brand names, Sibazon Analogs

Sibazon Brand Names Mixture

  • No information avaliable

Sibazon Chemical_Formula


Sibazon RX_link

Sibazon fda sheet

Sibazon msds (material safety sheet)

Sibazon MSDS

Sibazon Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Sibazon Molecular Weight

284.74 g/mol

Sibazon Melting Point


Sibazon H2O Solubility

Slightly soluble (50 mg/L)

Sibazon State


Sibazon LogP


Sibazon Dosage Forms

Tablets; Injectable solution

Sibazon Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Sibazon Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Sibazon Absorption

Essentially complete, with a bioavailability of 93%.

Sibazon side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Sibazon Patient Information

Sibazon Organisms Affected

Humans and other mammals