Paceum

Paceum Brand names, Paceum Analogs

Paceum Brand Names Mixture

No information avaliable

Paceum Chemical_Formula

C₁₆H₁₃ClN₂O

Paceum RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Paceum fda sheet

Paceum msds (material safety sheet)

Paceum MSDS

Paceum Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Paceum Molecular Weight

284.74 g/mol

Paceum Melting Point

125-126^oC

Paceum H₂O Solubility

Slightly soluble (50 mg/L)

Paceum State

solid

Paceum LogP

2.988

Paceum Dosage Forms

Tablets; Injectable solution

Paceum Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Paceum Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Paceum Absorption

Essentially complete, with a bioavailability of 93%.

Paceum side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Paceum Patient Information

Paceum Organisms Affected

Humans and other mammals