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Atensine Brand names, Atensine Analogs

Atensine Brand Names Mixture

  • No information avaliable

Atensine Chemical_Formula

C16H13ClN2O

Atensine RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Atensine fda sheet

Atensine msds (material safety sheet)

Atensine MSDS

Atensine Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Atensine Molecular Weight

284.74 g/mol

Atensine Melting Point

125-126oC

Atensine H2O Solubility

Slightly soluble (50 mg/L)

Atensine State

solid

Atensine LogP

2.988

Atensine Dosage Forms

Tablets; Injectable solution

Atensine Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Atensine Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Atensine Absorption

Essentially complete, with a bioavailability of 93%.

Atensine side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Atensine Patient Information

Atensine Organisms Affected

Humans and other mammals