Apozepam

Apozepam Brand names, Apozepam Analogs

Apozepam Brand Names Mixture

No information avaliable

Apozepam Chemical_Formula

C₁₆H₁₃ClN₂O

Apozepam RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Apozepam fda sheet

Apozepam msds (material safety sheet)

Apozepam MSDS

Apozepam Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Apozepam Molecular Weight

284.74 g/mol

Apozepam Melting Point

125-126^oC

Apozepam H₂O Solubility

Slightly soluble (50 mg/L)

Apozepam State

solid

Apozepam LogP

2.988

Apozepam Dosage Forms

Tablets; Injectable solution

Apozepam Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Apozepam Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Apozepam Absorption

Essentially complete, with a bioavailability of 93%.

Apozepam side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Apozepam Patient Information

Apozepam Organisms Affected

Humans and other mammals