Vivol

Vivol Brand names, Vivol Analogs

Vivol Brand Names Mixture

No information avaliable

Vivol Chemical_Formula

C₁₆H₁₃ClN₂O

Vivol RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Vivol fda sheet

Vivol msds (material safety sheet)

Vivol MSDS

Vivol Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Vivol Molecular Weight

284.74 g/mol

Vivol Melting Point

125-126^oC

Vivol H₂O Solubility

Slightly soluble (50 mg/L)

Vivol State

solid

Vivol LogP

2.988

Vivol Dosage Forms

Tablets; Injectable solution

Vivol Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Vivol Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Vivol Absorption

Essentially complete, with a bioavailability of 93%.

Vivol side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Vivol Patient Information

Vivol Organisms Affected

Humans and other mammals