Evacalm

Evacalm Brand names, Evacalm Analogs

Evacalm Brand Names Mixture

No information avaliable

Evacalm Chemical_Formula

C₁₆H₁₃ClN₂O

Evacalm RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Evacalm fda sheet

Evacalm msds (material safety sheet)

Evacalm MSDS

Evacalm Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Evacalm Molecular Weight

284.74 g/mol

Evacalm Melting Point

125-126^oC

Evacalm H₂O Solubility

Slightly soluble (50 mg/L)

Evacalm State

solid

Evacalm LogP

2.988

Evacalm Dosage Forms

Tablets; Injectable solution

Evacalm Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Evacalm Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Evacalm Absorption

Essentially complete, with a bioavailability of 93%.

Evacalm side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Evacalm Patient Information

Evacalm Organisms Affected

Humans and other mammals