Levium

Levium Brand names, Levium Analogs

Levium Brand Names Mixture

No information avaliable

Levium Chemical_Formula

C₁₆H₁₃ClN₂O

Levium RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Levium fda sheet

Levium msds (material safety sheet)

Levium MSDS

Levium Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Levium Molecular Weight

284.74 g/mol

Levium Melting Point

125-126^oC

Levium H₂O Solubility

Slightly soluble (50 mg/L)

Levium State

solid

Levium LogP

2.988

Levium Dosage Forms

Tablets; Injectable solution

Levium Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Levium Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Levium Absorption

Essentially complete, with a bioavailability of 93%.

Levium side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Levium Patient Information

Levium Organisms Affected

Humans and other mammals