Quetinil

Quetinil Brand names, Quetinil Analogs

Quetinil Brand Names Mixture

No information avaliable

Quetinil Chemical_Formula

C₁₆H₁₃ClN₂O

Quetinil RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Quetinil fda sheet

Quetinil msds (material safety sheet)

Quetinil MSDS

Quetinil Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Quetinil Molecular Weight

284.74 g/mol

Quetinil Melting Point

125-126^oC

Quetinil H₂O Solubility

Slightly soluble (50 mg/L)

Quetinil State

solid

Quetinil LogP

2.988

Quetinil Dosage Forms

Tablets; Injectable solution

Quetinil Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Quetinil Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Quetinil Absorption

Essentially complete, with a bioavailability of 93%.

Quetinil side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Quetinil Patient Information

Quetinil Organisms Affected

Humans and other mammals