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Kiatrium Brand names, Kiatrium Analogs

Kiatrium Brand Names Mixture

  • No information avaliable

Kiatrium Chemical_Formula

C16H13ClN2O

Kiatrium RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Kiatrium fda sheet

Kiatrium msds (material safety sheet)

Kiatrium MSDS

Kiatrium Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Kiatrium Molecular Weight

284.74 g/mol

Kiatrium Melting Point

125-126oC

Kiatrium H2O Solubility

Slightly soluble (50 mg/L)

Kiatrium State

solid

Kiatrium LogP

2.988

Kiatrium Dosage Forms

Tablets; Injectable solution

Kiatrium Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Kiatrium Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Kiatrium Absorption

Essentially complete, with a bioavailability of 93%.

Kiatrium side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Kiatrium Patient Information

Kiatrium Organisms Affected

Humans and other mammals