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Diazepan Brand names, Diazepan Analogs

Diazepan Brand Names Mixture

  • No information avaliable

Diazepan Chemical_Formula

C16H13ClN2O

Diazepan RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Diazepan fda sheet

Diazepan msds (material safety sheet)

Diazepan MSDS

Diazepan Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Diazepan Molecular Weight

284.74 g/mol

Diazepan Melting Point

125-126oC

Diazepan H2O Solubility

Slightly soluble (50 mg/L)

Diazepan State

solid

Diazepan LogP

2.988

Diazepan Dosage Forms

Tablets; Injectable solution

Diazepan Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Diazepan Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Diazepan Absorption

Essentially complete, with a bioavailability of 93%.

Diazepan side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Diazepan Patient Information

Diazepan Organisms Affected

Humans and other mammals