Amiprol

Amiprol Brand names, Amiprol Analogs

Amiprol Brand Names Mixture

No information avaliable

Amiprol Chemical_Formula

C₁₆H₁₃ClN₂O

Amiprol RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Amiprol fda sheet

Amiprol msds (material safety sheet)

Amiprol MSDS

Amiprol Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Amiprol Molecular Weight

284.74 g/mol

Amiprol Melting Point

125-126^oC

Amiprol H₂O Solubility

Slightly soluble (50 mg/L)

Amiprol State

solid

Amiprol LogP

2.988

Amiprol Dosage Forms

Tablets; Injectable solution

Amiprol Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Amiprol Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Amiprol Absorption

Essentially complete, with a bioavailability of 93%.

Amiprol side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Amiprol Patient Information

Amiprol Organisms Affected

Humans and other mammals