Gihitan

Gihitan Brand names, Gihitan Analogs

Gihitan Brand Names Mixture

No information avaliable

Gihitan Chemical_Formula

C₁₆H₁₃ClN₂O

Gihitan RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Gihitan fda sheet

Gihitan msds (material safety sheet)

Gihitan MSDS

Gihitan Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Gihitan Molecular Weight

284.74 g/mol

Gihitan Melting Point

125-126^oC

Gihitan H₂O Solubility

Slightly soluble (50 mg/L)

Gihitan State

solid

Gihitan LogP

2.988

Gihitan Dosage Forms

Tablets; Injectable solution

Gihitan Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Gihitan Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Gihitan Absorption

Essentially complete, with a bioavailability of 93%.

Gihitan side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Gihitan Patient Information

Gihitan Organisms Affected

Humans and other mammals