Sedapam

Sedapam Brand names, Sedapam Analogs

Sedapam Brand Names Mixture

No information avaliable

Sedapam Chemical_Formula

C₁₆H₁₃ClN₂O

Sedapam RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Sedapam fda sheet

Sedapam msds (material safety sheet)

Sedapam MSDS

Sedapam Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Sedapam Molecular Weight

284.74 g/mol

Sedapam Melting Point

125-126^oC

Sedapam H₂O Solubility

Slightly soluble (50 mg/L)

Sedapam State

solid

Sedapam LogP

2.988

Sedapam Dosage Forms

Tablets; Injectable solution

Sedapam Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Sedapam Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Sedapam Absorption

Essentially complete, with a bioavailability of 93%.

Sedapam side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Sedapam Patient Information

Sedapam Organisms Affected

Humans and other mammals