Apo-Diazepam

Apo-Diazepam Brand names, Apo-Diazepam Analogs

Apo-Diazepam Brand Names Mixture

No information avaliable

Apo-Diazepam Chemical_Formula

C₁₆H₁₃ClN₂O

Apo-Diazepam RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Apo-Diazepam fda sheet

Apo-Diazepam msds (material safety sheet)

Apo-Diazepam MSDS

Apo-Diazepam Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Apo-Diazepam Molecular Weight

284.74 g/mol

Apo-Diazepam Melting Point

125-126^oC

Apo-Diazepam H₂O Solubility

Slightly soluble (50 mg/L)

Apo-Diazepam State

solid

Apo-Diazepam LogP

2.988

Apo-Diazepam Dosage Forms

Tablets; Injectable solution

Apo-Diazepam Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Apo-Diazepam Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Apo-Diazepam Absorption

Essentially complete, with a bioavailability of 93%.

Apo-Diazepam side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Apo-Diazepam Patient Information

Apo-Diazepam Organisms Affected

Humans and other mammals