Noan

Noan Brand names, Noan Analogs

Noan Brand Names Mixture

No information avaliable

Noan Chemical_Formula

C₁₆H₁₃ClN₂O

Noan RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Noan fda sheet

Noan msds (material safety sheet)

Noan MSDS

Noan Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Noan Molecular Weight

284.74 g/mol

Noan Melting Point

125-126^oC

Noan H₂O Solubility

Slightly soluble (50 mg/L)

Noan State

solid

Noan LogP

2.988

Noan Dosage Forms

Tablets; Injectable solution

Noan Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Noan Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Noan Absorption

Essentially complete, with a bioavailability of 93%.

Noan side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Noan Patient Information

Noan Organisms Affected

Humans and other mammals