Methyldiazepinone
Methyldiazepinone Brand names, Methyldiazepinone Analogs
- Alboral
- Aliseum
- Alupram
- Amiprol
- An-Ding
- Ansiolin
- Ansiolisina
- Apaurin
- Apo-Diazepam
- Apozepam
- Armonil
- Assival
- Atensine
- Atilen
- Bensedin
- Bialzepam
- Calmocitene
- Calmpose
- Cercine
- Ceregulart
- Condition
- DAP
- Diacepan
- Dialag
- Dialar
- Diapam
- Diastat
- Diazemuls
- Diazemulus
- Diazepam Intensol
- Diazepan
- Diazetard
- Dienpax
- Dipam
- Dipezona
- Dizac
- Domalium
- Duksen
- Duxen
- E-Pam
- Eridan
- Eurosan
- Evacalm
- Faustan
- Faustan,
- Freudal
- Frustan
- Gewacalm
- Gihitan
- Horizon
- Kabivitrum
- Kiatrium
- LA III
- La-Iii
- Lamra
- Lembrol
- Levium
- Liberetas
- Mandrozep
- Methyldiazepinone
- Methyldiazepinone, Pharmaceutical
- Morosan
- Neurolytril
- Noan
- Novazam
- Novo-Dipam
- Paceum
- Pacitran
- Paranten
- Paxate
- Paxel
- Plidan
- Pms-Diazepam
- Pro-Pam
- Q-Pam
- Q-Pam Relanium
- Quetinil
- Quiatril
- Quievita
- Relaminal
- Relanium
- Relax
- Renborin
- Ruhsitus
- S.A. R.L.
- Saromet
- Sedapam
- Sedipam
- Seduksen
- Seduxen
- Serenack
- Serenamin
- Serenzin
- Servizepam
- Setonil
- Sibazon
- Sibazone
- Solis
- Sonacon
- Stesolid
- Stesolin
- Tensopam
- Tranimul
- Tranqdyn
- Tranquase
- Tranquirit
- Tranquo-Puren
- Tranquo-Tablinen
- Umbrium
- Unisedil
- Usempax Ap
- Valaxona
- Valeo
- Valiquid
- Valitran
- Valium
- Valrelease
- Vatran
- Velium
- Vival
- Vivol
- Zetran
- Zipan
Methyldiazepinone Brand Names Mixture
- No information avaliable
Methyldiazepinone Chemical_Formula
C16H13ClN2O
Methyldiazepinone RX_link
http://www.rxlist.com/cgi/generic/diazepam.htm
Methyldiazepinone fda sheet
Methyldiazepinone msds (material safety sheet)
Methyldiazepinone Synthesis Reference
Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)
Methyldiazepinone Molecular Weight
284.74 g/mol
Methyldiazepinone Melting Point
125-126oC
Methyldiazepinone H2O Solubility
Slightly soluble (50 mg/L)
Methyldiazepinone State
solid
Methyldiazepinone LogP
2.988
Methyldiazepinone Dosage Forms
Tablets; Injectable solution
Methyldiazepinone Indication
Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.
Methyldiazepinone Pharmacology
Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.
Methyldiazepinone Absorption
Essentially complete, with a bioavailability of 93%.
Methyldiazepinone side effects and Toxicity
Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.
Methyldiazepinone Patient Information
Methyldiazepinone Organisms Affected
Humans and other mammals
