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Methyldiazepinone Brand names, Methyldiazepinone Analogs

Methyldiazepinone Brand Names Mixture

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Methyldiazepinone Chemical_Formula


Methyldiazepinone RX_link

Methyldiazepinone fda sheet

Methyldiazepinone msds (material safety sheet)

Methyldiazepinone MSDS

Methyldiazepinone Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Methyldiazepinone Molecular Weight

284.74 g/mol

Methyldiazepinone Melting Point


Methyldiazepinone H2O Solubility

Slightly soluble (50 mg/L)

Methyldiazepinone State


Methyldiazepinone LogP


Methyldiazepinone Dosage Forms

Tablets; Injectable solution

Methyldiazepinone Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Methyldiazepinone Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Methyldiazepinone Absorption

Essentially complete, with a bioavailability of 93%.

Methyldiazepinone side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Methyldiazepinone Patient Information

Methyldiazepinone Organisms Affected

Humans and other mammals